King Duncan is murdered by Macbeth in Macbeth's castle. Of course, at the time in which the play is set there were no forensic capabilities, so it would be a lot harder to prove a murder than it is now. But, just of the sake of the question, if we assume that there are modern forensic tools available there are several things from the murder scene that might prove useful.
First, and most obviously, the...
King Duncan is murdered by Macbeth in Macbeth's castle. Of course, at the time in which the play is set there were no forensic capabilities, so it would be a lot harder to prove a murder than it is now. But, just of the sake of the question, if we assume that there are modern forensic tools available there are several things from the murder scene that might prove useful.
First, and most obviously, the daggers would need to be preserved and carefully analyzed. We would expect to find King Duncan's blood on them, but sometimes when someone is in the act of stabbing they also cut themselves on the blade, so you might try to find the presence the another person's blood. You could also check the daggers for fingerprints.
The glasses that were used to get the guards drunk could be preserved and analyzed. At one point Lady Macbeth says "I have drugged their possets." Maybe something in addition to the wine could be found in the residue in the glasses.
The door handle could be checked for fingerprints.
The clothing that the guards are wearing should be checked for King Duncan's blood, since they are initially suspected of the murder.
King Duncan's bedsheets should also be preserved and checked for hairs or DNA, since that could have been transferred from the killer in the act.
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